Why Scientists Are Studying the Coenzyme NAD plus link graphic Elysium link Mission link Science link Product Unlabeled graphic Unlabeled graphic To get missing image descriptions, open the context menu. The Science of NAD plus , Explained The coenzyme NAD plus the golden nucleotide is the subject of countless preclinical studies indicating that increasing NAD plus levels in lower organisms may have a variety of positive effects on health. We’re especially interested in NAD plus at Elysium: We’ve demonstrated that our first product, link Basis, increases NAD plus levels in humans , and we’re working on research to better understand how the gut microbiome affects systemic levels of NAD plus . If you’re new to the science of NAD plus , here are a few facts to get you started. Unlabeled graphic Unlabeled graphic d 6ee 8057 46d 6 41d 0 9532 384c 83… NAD plus is a coenzyme found in all living cells. Coenzymes are colloquially referred to as helper molecules because proteins    large molecules made of amino acids that do the important biological work in the body   require them to do their work. (And they’re called coenzymesbecause most proteins are enzymes.) If you think of a car as a protein, getting you from place to place so you can go about your life, the gas (or battery if you have a Tesla) is the coenzyme, without which driving is impossible. But gas (or batteries) can also be used to power any number of other things, from yachts to spacecraft. So too with NAD plus , whose chief role is transferring electrons in redox reactions, including oxidative phosphorylation, otherwise known as the metabolic process our body uses to turn food into energy. Nobel Prize winning scientists discovered NAD plus more than 100 years ago. NAD plus was first discovered by Arthur Harden and William John Young in 1906. In 1929, Harden and Hans von Euler Chelpin won the Nobel Prize in Chemistry for their work on fermentation. They determined that fermentation required the presence of an enzyme ( zymase, actually a mixture of enzymes) and a coenzyme which they called cozymase, now known as NAD plus . Euler Chelpin further identified the structure of NAD plus , which is made of two nucleotides, the building blocks for nucleic acids (the same thing DNA is made of). The role of NAD plus in fermentation, a metabolic process, foreshadowed the critical role that NAD plus plays in metabolic processes in humans. Unlabeled graphic Unlabeled graphic 0d 590a 10 c 4ce 48b 2 87b 3 757ed 8… The science of NAD plus is evolving as more research emerges. Several important discoveries about NAD plus followed the 1929 Nobel Prize. The most recent discovery happened at MIT, when link Dr. Leonard Guarente , founder of Elysium, and Dr. Shin ichiro Imai observed that sirtuins    a family of proteins that have been shown in the laboratory setting to be influential in impacting healthspan    only function in the presence of NAD plus . (Reminder: Sirtuins are the proteins that do biological work; NAD plus is the coenzyme that allows that work to happen.) So why are scientists excited? An increasingly detailed picture of NAD plus shows its many functions, from energy creation, to sirtuin activity, to a wide range of other enzymatic activities including mitochondrial function, chromosomal integrity, gene expression, epigenetic and posttranslational modifications, and calcium signaling. link Learn How Basis Increases NAD plus Unlabeled graphic Unlabeled graphic f 625c 778 ccc 9 4041 881c ec 6438… link graphic Elysium Copyright 2017 Elysium Health Inc dot , P dot O. Box 923, New York, NY 10013 Contact us: link (888) 220 6436 or link email protected link Unsubscribe These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease, and is intended for healthy adults, 18 years of age or older. Do not take this product if you are pregnant or nursing.